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Aicar Australia SARM Steroids AICA-RIBOSIDE Z-RIBOSIDE AMPK Treating Cardiovascular Diseases 2627-69-2
AICAR Quack Detail
Product Name: AICAR
Synonyms: ACADESINE;AICAR;AICA-RIBOSIDE;AMPK;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-RIBOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-B-D-RIBOFURANOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE 1-BETA-D-RIBOFURANOSIDE;Z-RIBOSIDE
AICAR is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in.
AICAR’s principal mechanism of action is activation of AMPK (AMP-activated protein kinase.) Activating AMPK, therefore, causes the same cellular machinery (so to speak) to be turned on as if the cell were energy deprived, for example from intensive exercise, or from low caloric intake.
AICAR, at sufficient and quite substantial concentration, is effective at activating AMPK and inducing a cellular state as if exercise had been performed, or energy stores were low and fat therefore needed to be burned.
AIRCAR, also known as acadesine, is a synthetic adenosine monophosphate (AMP) analog that activates
activated protein kinase (AMPK), which plays a role in cellular energy homeostasis; ATP (adenosine
triphosphate) is produced by mitochondria as a readily available energy source for chemical processes in
the cell. When cells become energy deprived, AMP accumulates. When the cell detects any low energy
state from the concentration of AMP present, AMPK is activated. The activation of AMPK increases the
conversion of fuel sources, such as fatty acids, into ATP. Activating AMPK causes the same processes to
occur that take place when the cell is energy deprived from exercise or low calorie intake. AIRCAR has
been shown to be effective at activating AMPK as if exercise was performed, or energy stores were low
and fat needed to be burned as fuel.
AICAR works best as part of an endurance stack, and it has been used by athletes as a performance
enhancing compound in sports, where endurance is needed.
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
|Test Pro||CJC-1295 with DAC|
|Mast Enan||CJC-1295 without DAC|
|Related substance (HPLC)||Total impurity ≤0.5%
Max single impurity ≤0.1%
|Sieve analysis||100% pass 80 mesh||Complies|
|Loss on Drying
Residue on Ignition
|Total Plate Count||<1000cfu/g||Complies|
|Yeast & Mold||<100cfu/g||Complies|
About powder quality
Our product is powders and liquids, the purity of the powder is 99%, so many customers are satisfied with our quality, they often buy our powders. at the some times, They will sell liquid, yes, brother, they make a lot of money.
About liquid quality
Clarity of the liquid is very high, there are many customers think the powder is very complex, so they can directly buy our liquid effect is very good! of course,you buy our powder, we can tell you the method of making the liquid If you buy a liquid, we will tell you how to filter
About Safe transportation
Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 4-7 to your product.
Our strength :
Our team consist of Chemical researchers and QC inspection team.Each batch of goods are strictly controlled.We only export Safe and Pure steroids.
Our factory covers an area of 33,500 square meters with the advanced technology equipment,and our monthly output is over 100kgs,which ensures prompt delivery.
100% factory direct supply comfirms that we have price advantages over peers.